This is a list of companies either based or with large operations in the Philadelphia and greater Delaware Valley region area of the United States.
Active companies headquartered in the region
Nonprofit companies headquartered in the region
US headquarters of foreign corporations
Divisions of US corporations
Divisions of foreign corporations
Defunct corporations
Corporations that moved to a different region
- Amkor Technology - moved from West Chester, Pennsylvania to Chandler, Arizona
- Bell Atlantic - after merger with NYNEX, headquarters moved from Philadelphia to New York City; a significant workforce remains in the area
- Breyers - acquired by Kraft Foods and then by Unilever
- Jones Apparel Group - moved to New York City
- Whitman's - now operated by Russell Stover; based in Colorado
Less notable Philadelphia corporations
- Burnt Toast Vinyl
- Campus Apartments
- Day's Beverages
- Yards Brewing Company
- Zivtech - software and web development
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